Shamaki B Usman
University of Maiduguri, Nigeria
Title: Novel ethno-therapeutic agent against squamous cell carcinoma in sheep using wild Ganoderma species based petrolatum paste in Nigeria
Biography
Biography: Shamaki B Usman
Abstract
Squamous Cell Carcinoma (SCC) or skin cancer is the most common type of cancer in animals worldwide. There are claims of anticancer potentials of the wild Ganoderma sp., that is currently undergoing research, however, most of these researches involved in vitro studies methods using cell lines. Three sheep (Balami breed) were observed with cauliflower-like growths on various locations on their skins, and histopathological analysis from the skin biopsies revealed that it was squamous cell carcinoma. Using wild Ganoderma sp. based jelly at 6.7 mg/Ml. It was applied daily for two consecutive weeks on the specific growth areas on the treated sheep, while one of the sheep served as positive control with only the petrolatum jelly applied for the same period and the third sheep served as negative control and was not administered any topical treatment. Results from this study showed progressive regression of the tumorous growth in the treated sheep following topical application of the Ganoderma sp., based jelly treatment until completely cured after two weeks of topical application, while progressive growth of the tumor on the skin of both controls was observed within the same treatment periods. In conclusion, this study demonstrated that wild Ganoderma sp., based petrolatum paste preparation alone, can cure squamous cell carcinoma in sheep when compared to the control and may be a potential novel, ethno-therapy based anticancer agent for veterinary use.