Oncology and Cancer

Breast cancer and cell biology

Breast cancer arises from abnormal cell growth in the breast tissue, influenced by complex biological mechanisms. Normal breast cells undergo regulated growth and division, but genetic mutations can disrupt these processes, leading to cancerous growth. Understanding the cell biology of breast cancer involves studying how these mutations, such as in genes like BRCA1 and BRCA2, contribute to tumor development and progression. Factors like hormone receptor status (estrogen, progesterone, and HER2), tumor microenvironment, and immune system interactions play critical roles in shaping the disease's behavior and response to treatment. Research into these mechanisms guides the development of targeted therapies, including hormone therapies and HER2-targeted treatments, aimed at disrupting cancer cell growth pathways. By unraveling the complexities of breast cancer cell biology, we advance towards more effective treatments and personalized care strategies for patients.