Novel Therapeutic Targets:

In breast cancer research, scientists are constantly searching for new "targets" within cancer cells that can be treated with therapies. These targets are specific molecules or pathways that play a key role in cancer growth and spread. Identifying novel therapeutic targets helps develop treatments that can precisely attack cancer cells while sparing healthy tissue.

For instance, researchers are studying the PI3K/AKT/mTOR pathway, commonly altered in breast cancer, as a potential target for drugs. Another target is the HER2 protein, overexpressed in some breast cancers, leading to drugs like trastuzumab.

Emerging targets such as CDK4/6 inhibitors are showing promise, particularly in hormone receptor-positive breast cancer. By understanding these targets, scientists develop new drugs to block or interfere with them, disrupting cancer growth.

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